RESUMO
Peripheral blood T and B lymphocyte percentage and serum immunoglobulin levels were evaluated in 36 Maculo-anaesthetic (MA) leprosy patients using E and EAC rosette techniques and single radial immuno-diffusion respectively. 21 Tuberculoid, 13 Indeterminate, 16 Borderline, 13 Lepromatous and 20 healthy controls were also studied for comparison. The results showed that the peripheral blood T lymphocyte percentages and humoral immune responses of Maculoanaesthetic leprosy are not significantly different from either Tuberculoid or Indeterminate leprosy types or from control group.
Assuntos
Imunoglobulinas/análise , Hanseníase/imunologia , Contagem de Leucócitos , Linfócitos/imunologia , Linfócitos B/imunologia , Humanos , Imunoglobulina A/análise , Imunoglobulina G/análise , Imunoglobulina M/análise , Hanseníase/diagnóstico , Formação de Roseta , Linfócitos T/imunologiaRESUMO
M. leprae-specific cell-mediated immune responses were studied in 36 Maculoanaesthetic (MA) leprosy patients using Leucocyte Migration Inhibition Test (LMIT). 21-Tuberculoid, 13-Indeterminate, 16-Borderline, 13-Lepromatous and 20-Healthy controls were also studied for comparison. Highly significant differences (p less than 0.001) in the mean Migratory Indices (M.I.) were found between MA leprosy type and each of the other leprosy type or control group. The results support the concept that MA type forms a distinct form of leprosy from tuberculoid type or any other type of leprosy.